The Clinical Proteomics Tumor Analysis Consortium (CPTAC)- Data Center
The Clinical Proteomic Tumor Analysis Consortium (CPTAC) of NCI’s Office of Cancer Clinical Proteomics Research, is a comprehensive and coordinated effort to accelerate the understanding of the molecular basis of cancer through the application of proteomic technologies and workflows to tumor samples with characterized genomic and transcript profiles. The combination of proteomics, transcriptomics, and genomics data from the same tumor samples provides an unprecedented opportunity for tumor proteogenomics as illustrated by several consortium wide high-profile Nature and Cell publications.
The CPTAC Data Portal (cptac-data-portal.georgetown.edu) is the public repository for dissemination of proteomic data collected by CPTAC. The portal currently hosts over 50 TB of data and includes proteomic investigations of breast, colorectal, and ovarian TCGA tumor tissue. This year Georgetown developed cloud based Common Data Analysis Pipeline (CDAP) for proteomics to use on CPTAC MS/MS data (manuscript in preparation). This data and the team are an integral part of NCI’s Cancer Research data Commons (CRDC).
Collaborating partner: ESAC Inc., A disadvantaged Small Business